Drug intelligence / Profile preview

Tears Naturale Free + Refresh Single Dose Eye Drop

Development stage
Unknown
Lead developer
Alcon
Modality
Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Small Molecules, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
Administration
Ophthalmic
01

Overview

Tears Naturale Free + Refresh Single Dose Eye Drop refers to a combination or concurrent use of two prominent preservative-free lubricant eye drop brands: **Tears Naturale Free** (developed by Alcon) and **Refresh** (developed by Allergan/AbbVie). Tears Naturale Free utilizes the Duasorb polymeric system, consisting of Dextran 70 and Hypromellose (Hydroxypropyl Methylcellulose), which mimics natural tears to provide relief from dry eye symptoms. The Refresh line, particularly Refresh Plus or Refresh Tears, typically utilizes Carboxymethylcellulose sodium as its active lubricant. Both products are formulated without preservatives to minimize irritation, making them suitable for sensitive eyes or frequent use. They work by increasing tear film stability and providing a protective moisture barrier on the ocular surface to alleviate dryness and irritation.

Brand names
RefreshRefresh PlusRefresh Tears
Other names
Tears Naturale Free Lubricant Eye DropsRefresh Plus Lubricant Eye DropsDextran 70 + HypromelloseCarboxymethylcellulose sodium

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