Drug intelligence / Profile preview

Techglim-M2 Forte

Development stage
Phase 4
Lead developer
Cytech Pharma
Modality
Small Molecules
Administration
Oral
01

Overview

Techglim-M2 Forte is an oral fixed-dose combination tablet containing glimepiride (2 mg) and sustained-release metformin (1000 mg), developed by Cytech Pharma for the management of type 2 diabetes mellitus. Glimepiride is a second-generation sulfonylurea that stimulates insulin secretion from pancreatic beta cells by binding to sulfonylurea receptors and closing ATP-sensitive potassium channels. Metformin is a biguanide that improves glycemic control by decreasing hepatic glucose production, reducing intestinal glucose absorption, and enhancing insulin sensitivity in peripheral tissues. Together, these agents provide complementary mechanisms of action to effectively lower blood glucose levels in patients whose diabetes is not adequately controlled by diet, exercise, or monotherapy.

Brand names
Techglim M2FTechglim-M2 ForteTechglim-M-2 ForteTechglim-M 2 ForteTechglim-M2FTechglim-M-2FTechglim-M 2F
Other names
glimepiride + metforminglimepiride + metformin sustained releaseglimipiride + metformin
02

Targets

SUR1 (Sulfonylurea receptor 1)AMPK (Adenosine monophosphate–activated protein kinase)ND1 (Mitochondrial electron transport chain complex I)TFF1 (Trefoil factor 1)KCNJ11 (Atp-sensitive inward rectifier potassium channel 11)GSEC (Gamma-Secretase Complex)

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