Drug intelligence / Profile preview

TECHIDA

Development stage
Unknown
Lead developer
Izotop
Modality
Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

TECHIDA is a diagnostic radiopharmaceutical cold kit developed by Izotop (Institute of Isotopes Co. Ltd.) for use in Single Photon Emission Computed Tomography (SPECT) imaging of the hepatobiliary system. The kit contains 30 mg of etifenin (diethyl-acetanilid-imino diacetic acid) as the active ligand. Upon reconstitution with sodium pertechnetate (99mTc), it forms the Technetium (99mTc) etifenin complex. This complex is an iminodiacetic acid (IDA) derivative that mimics the metabolic pathway of bilirubin; it is rapidly cleared from the blood by hepatocytes and excreted into the biliary tract. TECHIDA is primarily indicated for the dynamic examination of hepatocyte function, evaluation of liver transplants, diagnosis of acute cholecystitis, and the assessment of biliary flow disorders such as ductal blockages.

Brand names
TECHIDA
Other names
Technetium (99mTc) etifeninetifenindiethyl-acetanilid-imino diacetic acidTECHIDA 30 mg kitTECHIDA30 mg kitTECHIDA-30 mg kit
02

Targets

OATP (Organic anion transporting polypeptides)

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