Drug intelligence / Profile preview

technetium (99mTc) macrosalb

Development stage
Unknown
Lead developer
Medi-Radiopharma
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Gamma Emitters → Radiopharmaceuticals
Administration
Intravenous
01

Overview

Medi-MAA is a diagnostic radiopharmaceutical cold kit containing 2.5 mg of macroaggregated human serum albumin (macrosalb). Upon reconstitution and radiolabeling with sodium pertechnetate (99mTc) solution, it forms technetium (99mTc) macrosalb. The diagnostic agent is administered intravenously, where the macroaggregated particles temporarily lodge in the pulmonary capillary bed via physical microembolisation. This allows for scintigraphic imaging of pulmonary perfusion to evaluate conditions such as pulmonary embolism, chronic circulatory failure, emphysema, and venous circulation disorders.

Brand names
Medi-MAA
Other names
99mTc-HSA macroaggregated human albumin99mTc-MAAhuman serum albumin macroaggregatehuman serum albumin macroaggregatesmacroaggregated human albuminmacrosalb (99m Tc)technetium (99mTc) albumin macroaggregatestechnetium tc 99m macrosalbtechnetium-99m macroaggregated albumintechnetium99m macroaggregated albumintechnetium 99m macroaggregated albumin

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