Drug intelligence / Profile preview

technetium-99m + diethylenetriaminepentaacetic acid (Cliniques universitaires Saint-Luc)

Development stage
Unknown
Lead developer
PDRadiopharma
Modality
Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Inhalation
01

Overview

Technetium-99m diethylenetriaminepentaacetic acid (99mTc-DTPA) is a radioactive diagnostic tracer used for medical imaging, particularly in evaluating lung ventilation and aerosol distribution. It consists of the gamma-emitting radioisotope technetium-99m chelated by diethylenetriaminepentaacetic acid (pentetic acid). In the clinical research context at Cliniques universitaires Saint-Luc, the tracer is administered as a nebulized aerosol to healthy volunteers to compare the efficiency and distribution patterns of different nebulizer systems (vibrating-mesh vs. jet nebulizers) using Single Photon Emission Computed Tomography (SPECT-CT). The complex is highly stable and, when inhaled, allows for the visualization of regional lung ventilation and the assessment of alveolar-capillary membrane permeability.

Other names
technetium-99m pentetatetechnetium99m pentetatetechnetium 99m pentetate99mTc-pentetic acidtechnetium-99m diethylenetriaminepentaacetic acidtechnetium99m diethylenetriaminepentaacetic acidtechnetium 99m diethylenetriaminepentaacetic acid

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