Drug intelligence / Profile preview

technetium-99m stannous colloid

Development stage
Unknown
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Gamma Emitters → Radiopharmaceuticals
Administration
Intravenous
01

Overview

**Technetium-99m stannous colloid** is a diagnostic radiopharmaceutical consisting of technetium-99m associated with stannous colloid particles. It is used principally to label autologous leukocytes ex vivo for white-cell scintigraphy. Neutrophils and monocytes phagocytose the colloid, after which the radiolabeled cells can localize to inflammatory or infectious sites and be detected by gamma-camera imaging. Published studies describe its use for imaging inflammation, occult infection, inflammatory bowel disease activity, and gram-negative infection-associated alterations in leukocyte phagocytic function. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/15691667/))

Other names
99mTc Sn colloid99mTc SnC99mTc-stannous colloidtechnetium Tc 99m tin colloidtechnetium-99m stannous colloidtechnetium99m stannous colloidtechnetium 99m stannous colloidtechnetium-99m tin colloidtechnetium99m tin colloidtechnetium 99m tin colloid
02

Targets

αMβ2 (Integrin αMβ2)

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