tedizolid

Tedizolid is an oxazolidinone-class antibiotic that inhibits bacterial protein synthesis. It works by binding to the 50S subunit of bacterial ribosomes, preventing the formation of the functional 70S ribosomal subunit and thereby blocking bacterial protein synthesis. Tedizolid is 4-to-16-fold more potent against staphylococci and enterococci compared to linezolid. It was developed to treat acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible bacteria, including methicillin-resistant Staphylococcus aureus (MRSA).

Brand names

Sivextro

Other names

(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate