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Tegillidine is an analgesic agent currently under clinical investigation in China for the management of postoperative pain. It is being evaluated as a component of patient-controlled intravenous analgesia (PCIA) regimens, particularly following orthopedic procedures such as unilateral knee arthroplasty. In clinical trials, it has been compared to standard opioids like sufentanil to assess its analgesic efficacy, safety profile, and impact on rescue medication requirements. The drug is being developed and studied by institutions including The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University.
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