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TEI-W00595 is a metabolite of TCK-276, an investigational orally administered small molecule developed for the treatment of rheumatoid arthritis. TCK-276 undergoes metabolic conversion in the body to produce TEI-W00595, which is analyzed in clinical studies for its pharmacokinetic properties including plasma concentration, distribution, elimination half-life, and metabolic ratio. TEI-W00595 is not administered directly but is formed following oral dosing of TCK-276. The precise mechanism of action for TEI-W00595 is not detailed in public sources, but it is studied as part of the pharmacokinetic and safety evaluation of TCK-276 in rheumatoid arthritis patients[3].
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