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Telipro AM

Development stage: Unknown
Lead developer: Docventures
Modality: Small Molecules
Administration: Oral

Overview

Telipro AM is a fixed-dose combination antihypertensive medication developed and marketed by Docventures Pharmaceuticals. It contains two active small molecule ingredients: telmisartan (40 mg) and amlodipine (5 mg). Telmisartan is an angiotensin II receptor blocker (ARB) that selectively binds to the AT1 receptor, inhibiting the vasoconstrictive and aldosterone-secreting effects of angiotensin II. Amlodipine is a dihydropyridine calcium channel blocker (CCB) that inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle, leading to peripheral vasodilation. Together, these mechanisms work synergistically to lower blood pressure by relaxing blood vessels and reducing peripheral resistance, making it easier for the heart to pump blood around the body.

Brand names: Telipro AM
Other names: telmisartan + amlodipine

Targets

CACNA1C (Voltage-dependent L-type calcium channel subunit alpha-1C)AGTR1 (Angiotensin II Type-1 receptor)

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