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temazepam + choline
- Development stage
- Approved
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Temazepam + choline is a combination drug product containing temazepam and choline. Temazepam is a short-acting benzodiazepine that acts as a gamma-aminobutyric acid (GABA) modulator, enhancing the inhibitory effects of GABA in the central nervous system by binding to benzodiazepine receptors on GABA(a) receptors. This increases chloride ion conductance, resulting in hyperpolarization of neuron membranes and reduced neuronal excitation, producing sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, and anxiolytic effects. The combination with choline appears to be formulated as a kit for the management of insomnia, though the specific role of choline in this combination is not fully detailed in the available information. The product is marketed under the brand name Strazepam.
- Brand names
- Strazepam
- Other names
- choline bitartrate + temazepamSentra PM + temazepam
02
Targets
GABRR (GABA-A receptor subunit rho)
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