Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
TenecteRel
- Development stage
- Unknown
- Lead developer
- Reliance Life Sciences
- Modality
- Therapeutic Enzymes → Recombinant Proteins and Enzymes
- Administration
- Intravenous
01
Overview
TenecteRel is a recombinant thrombolytic agent developed and marketed by Reliance Life Sciences in India. It is a biosimilar of tenecteplase, a third-generation tissue plasminogen activator (tPA) variant produced using recombinant DNA technology in Chinese Hamster Ovary (CHO) cells. Tenecteplase is a 527 amino acid glycoprotein with specific amino acid substitutions in the kringle-1 and protease domains that confer high fibrin specificity and increased resistance to plasminogen activator inhibitor-1 (PAI-1). Its mechanism of action involves binding to fibrin-bound plasminogen and converting it to plasmin, which then degrades fibrin clots. TenecteRel is indicated for the reduction of mortality associated with acute myocardial infarction (AMI) and is administered intravenously as a weight-based single bolus dose over five seconds.
- Brand names
- TenecteRel
- Other names
- tenecteplase
02
Targets
Fibrin (Factor Ia)PLG (Plasminogen)
Beyond the preview
Go deeper on TenecteRel.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on TenecteRel.