teneligliptin + metformin

Teneligliptin + metformin is a fixed-dose combination of two oral antidiabetic agents used for the management of type 2 diabetes mellitus in adults when diet and exercise alone do not provide adequate glycemic control. Metformin is a biguanide that lowers blood glucose by decreasing hepatic glucose production (gluconeogenesis), reducing intestinal absorption of glucose, and increasing insulin sensitivity in peripheral tissues. Teneligliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that increases insulin secretion from pancreatic beta cells and decreases glucagon levels by inhibiting the DPP-4 enzyme responsible for degrading incretin hormones. This dual mechanism results in improved glycemic control by targeting both fasting and postprandial blood sugar levels[1][5][8]. The combination is indicated as an adjunct to diet and exercise for patients with type 2 diabetes who are inadequately controlled on metformin or teneligliptin monotherapy.

Brand names

Zita-Met PlusZiten-MDynaglipt-MTenglyn MTenepride MEternex-MTiban MMegagliptin MJaril MTenali M

Other names

Metformin + Teneligliptin