Drug intelligence / Profile preview

terpene-enriched medical cannabis oil

Development stage
Phase 3
Lead developer
Bazelet Group
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral, Sublingual
01

Overview

Terpene-enriched medical cannabis oil is a standardized, patented botanical formulation developed by Bazelet Group in collaboration with Hadassah Hebrew University Medical Center. It consists of medical cannabis oil (containing cannabinoids such as THC and CBD) enriched with a precise, optimized profile of specific cannabis-derived terpenes (such as myrcene, pinene, limonene, and beta-caryophyllene) to restore the volatile terpenes lost during standard extraction processes. This formulation leverages the 'entourage effect'—the synergistic interaction between cannabinoids and terpenes—to enhance therapeutic efficacy. It is primarily being evaluated in Phase 2 clinical trials for the management of chronic pain, acute radicular pain, attention-deficit/hyperactivity disorder (ADHD), and autism spectrum disorder (ASD), aiming to improve pain relief and reduce opioid dependence.

Brand names
BCANNBCANN SilverBCANN SpecialsFemmican
Other names
terpene-enhanced cannabinoid formulationterpene-enriched cannabinoid compositionterpene-enriched cannabis oil
02

Targets

CNR1 (Cannabinoid receptor 1)CNR2 (Cannabinoid receptor type 2)TRPV1 (Transient receptor potential cation channel subfamily V member 1)

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