Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
TEST 2-Center for Health Sciences, Serbia
- Development stage
- Unknown
- Lead developer
- Center for Health Sciences, Serbia
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
TEST 2 is an experimental multi-ingredient combination developed by the Center for Health Sciences in Serbia for use in clinical research. It consists of guanidinoacetic acid (GAA), choline dihydrogencitrate, vitamin B12, vitamin B6, and folic acid. The formulation is designed to evaluate the metabolic impact of GAA loading on plasma total homocysteine (T-HCy) levels in healthy individuals. GAA is a natural precursor to creatine, and its conversion via methylation in the liver consumes methyl groups from S-adenosylmethionine, which can lead to hyperhomocysteinemia. The inclusion of methyl donors (choline and folic acid) and B-vitamin cofactors (B6, B12) in the TEST 2 formulation is intended to support the remethylation and transsulfuration pathways, thereby attenuating the rise in homocysteine associated with GAA supplementation.
- Other names
- GAA + choline + B12 + B6 + folic acid
02
Targets
1C metabolism (One-carbon metabolism)GAMT (Guanidinoacetate N-methyltransferase)CBS (Cystathionine beta-synthase)BHMT (Betaine-homocysteine S-methyltransferase)
Beyond the preview
Go deeper on TEST 2-Center for Health Sciences, Serbia.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on TEST 2-Center for Health Sciences, Serbia.