Drug intelligence / Profile preview

testosterone + estradiol

Development stage
Phase 3
Lead developer
Mattern Pharma
Modality
Small Molecules
Administration
Intramuscular, Subcutaneous, Topical, Oral
01

Overview

Testosterone + estradiol is a combination hormone therapy that contains both testosterone and estradiol (a form of estrogen). This combination is used to treat menopausal symptoms in women who do not get adequate relief from estrogen therapy alone. Estradiol helps replace the natural estrogen that decreases during menopause, relieving symptoms like hot flashes, night sweats, and vaginal dryness. Testosterone helps address symptoms related to decreased testosterone levels that can occur during menopause. The combination is typically given cyclically (e.g., three weeks on, one week off) and for short-term use only.

02

Targets

AR (Adrenergic receptors)ER (Estrogen receptor)SHBG (Sex hormone-binding globulin)

Beyond the preview

Go deeper on testosterone + estradiol.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on testosterone + estradiol.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call