Drug intelligence / Profile preview

testosterone + estradiol

Development stage
Unknown
Lead developer
Mattern Pharma
Modality
Small Molecules
Administration
Intramuscular, Subcutaneous, Topical, Oral
01

Overview

Testosterone + estradiol is a combination hormone therapy that contains both testosterone and estradiol (a form of estrogen). This combination is used to treat menopausal symptoms in women who do not get adequate relief from estrogen therapy alone. Estradiol helps replace the natural estrogen that decreases during menopause, relieving symptoms like hot flashes, night sweats, and vaginal dryness. Testosterone helps address symptoms related to decreased testosterone levels that can occur during menopause. The combination is typically given cyclically (e.g., three weeks on, one week off) and for short-term use only.

02

Targets

SHBG (Sex hormone-binding globulin)ER (Estrogen receptor)AR (Adrenergic receptors)

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