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Testoviron Depot is an oil-based injectable formulation containing a combination of two testosterone esters: testosterone propionate and testosterone enanthate. Manufactured by Bayer, it acts as an androgen receptor agonist. Upon intramuscular administration, the esters are hydrolyzed to release testosterone, which then binds to androgen receptors to drive the development of masculine sex organs and secondary sexual characteristics. It is indicated for male hypogonadism, delayed puberty in boys, and breast carcinoma in women. The formulation produces a depot effect, with testosterone levels peaking shortly after injection and gradually declining until the next dose. It is currently being evaluated in a multicenter randomized Phase 2 trial in Sweden for pubertal replacement therapy in boys with absent or delayed puberty.
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