Drug intelligence / Profile preview

Tetadif

Development stage
Unknown
Lead developer
BulBio-NCIPD
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

Tetadif is an adsorbed tetanus-diphtheria toxoid (Td) vaccine with reduced-dose diphtheria content, developed and manufactured by the Bulgarian state-owned company BB-NCIPD Ltd (BulBio). The vaccine is a combination biologic containing purified tetanus and diphtheria toxoids adsorbed onto an aluminum hydroxide gel adjuvant, with thiomersal included as a preservative. It is specifically formulated for the active immunization of adults and children aged 7 years and older against tetanus and diphtheria. The vaccine works by inducing the production of neutralizing antibodies against the tetanus toxin produced by *Clostridium tetani* and the diphtheria toxin produced by *Corynebacterium diphtheriae*. Tetadif has been WHO prequalified since 2006 and serves as a significant supplier for global immunization programs through UNICEF.

Brand names
Tetadif
Other names
tetanus + diphtheria vaccinetetanus+diphtheriaTd vaccineAdsorbed tetanus-diphtheria toxoid vaccine
02

Targets

Diphtheria toxin

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