Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
tetanus and diphtheria vaccine-Baylor College of Medicine-tetanus-diphtheria
- Development stage
- Approved
- Lead developer
- Baylor College of Medicine
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
tetanus and diphtheria vaccine-Baylor College of Medicine-tetanus-diphtheria refers to a specific bivalent vaccine formulation utilized in clinical research conducted by Baylor College of Medicine. This vaccine is composed of 2 ug of tetanus toxoid (TT) and 2 ug of diphtheria toxoid (DT), adsorbed onto 3000 ug of an aluminum hydroxide (alum) adjuvant. It is primarily employed in Phase 1 pilot studies (such as NCT01843608) to investigate the safety and immunogenicity of novel vaccine adjuvants, specifically the TLR5 agonist entolimod (CBLB502). The vaccine aims to induce protective immunity against *Clostridium tetani* and *Corynebacterium diphtheriae* by stimulating the production of neutralizing antibodies against their respective toxins. The Baylor College of Medicine studies specifically evaluate whether the addition of entolimod can significantly augment the antibody response compared to the standard alum-adsorbed Td vaccine formulation.
- Other names
- Td vaccineTetanus-diphtheria vaccineTd vaccine (Baylor College of Medicine)
02
Targets
Diphtheria toxin
Beyond the preview
Go deeper on tetanus and diphtheria vaccine-Baylor College of Medicine-tetanus-diphtheria.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on tetanus and diphtheria vaccine-Baylor College of Medicine-tetanus-diphtheria.