Drug intelligence / Profile preview

tetanus toxoid alum precipitated

Development stage
Approved
Lead developer
Adimmune
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

Tetanus toxoid alum precipitated is a vaccine formulation designed to provide active immunity against tetanus, a serious disease caused by the toxin-producing bacterium *Clostridium tetani*. The vaccine contains tetanus toxoid—a chemically inactivated form of the tetanus toxin—which is adsorbed onto an aluminum-based adjuvant (alum) to enhance the immune response and prolong the duration of protection. Upon administration, the vaccine stimulates the production of specific antitoxin antibodies that neutralize the tetanus toxin, thereby preventing the clinical manifestations of the disease. Adimmune (formerly Kuo Kwang Biotechnology) is developing this specific alum-precipitated formulation, which is currently in the registration phase (NDA/BLA) for the prevention of tetanus.

Brand names
Kuo Kwang
Other names
tetanus toxoid alum precipitatedtetanus toxoid adsorbedadsorbed tetanus toxoidtetanus vaccine
02

Targets

TT-Al (Tetanus toxoid-adsorbed aluminum adjuvant)NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)

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