Drug intelligence / Profile preview

TETRActHib

Development stage
Approved
Lead developer
Sanofi
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

TETRActHib is a quadrivalent combination vaccine developed by Aventis Pasteur (now Sanofi) to provide active immunization against diphtheria, tetanus, pertussis, and invasive diseases caused by *Haemophilus influenzae* type b (Hib). The vaccine formulation includes diphtheria and tetanus toxoids, a whole-cell pertussis (wP) component, and a conjugated Hib component (PRP-T), typically adsorbed onto an aluminum salt adjuvant such as aluminum phosphate. It is designed for pediatric use, often as part of the Expanded Program on Immunization (EPI) in various regions. In clinical research, TETRActHib has been utilized as a standard-of-care comparator or co-administered vaccine in trials evaluating novel candidates, such as the RTS,S malaria vaccine, to ensure that the introduction of new vaccines does not interfere with the safety or immunogenicity of routine childhood immunizations.

Brand names
TETRActHib
Other names
Tetract-HibDTPw-Hib vaccineDTPw/Hib
02

Targets

Diphtheria toxinPRNP (Cellular Prion Protein)

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