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tetracycline + lidocaine
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Intrapleural, Topical
01
Overview
A combination of tetracycline, a bacteriostatic antibiotic that inhibits bacterial protein synthesis and matrix metalloproteinases, with lidocaine, an amide-type local anesthetic that blocks sodium ion channels. This combination is primarily used for pleurodesis procedures to treat pleural effusions and pneumothorax, and in topical applications for pain relief during dermatological procedures.
02
Targets
Bacterial RibosomeMMP12 (Macrophage Metalloelastase)NaV alpha (Voltage-gated sodium channel alpha subunit family)SCN10A (Sodium channel protein type X alpha subunit)
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