Drug intelligence / Profile preview

TGFBI gene therapy

Development stage
Preclinical
Lead developer
GenEditBio
Modality
Gene Therapies
Administration
Ophthalmic
01

Overview

TGFBI gene therapy is a therapeutic approach under clinical investigation for the treatment of corneal dystrophy, specifically TGFBI Stromal Corneal Dystrophy. This gene therapy aims to target the TGFBI gene, which is known to be involved in the pathology of this corneal disorder. It is being studied as an adjuvant to phototherapeutic keratectomy (PTK).

02

Targets

TGFBI (Transforming growth factor-beta-induced protein ig-h3)

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