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TGFP
- Development stage
- Unknown
- Lead developer
- China Medical University Hospital
- Administration
- Oral
01
Overview
TGFP (also referred to as TGF) is an herbal formula based on the traditional Chinese medicine **Hu-Qian Wan** (Hidden Tiger Pill), which is being developed by **China Medical University Hospital** for the treatment of **knee osteoarthritis**. The formula is a multi-ingredient botanical product traditionally used to nourish kidney yin and strengthen bones and tendons. In clinical studies, TGFP is being evaluated for its ability to reduce pain and improve joint function by modulating biochemical markers associated with cartilage degradation and inflammation, such as interleukin-1 (IL-1), interleukin-6 (IL-6), matrix metalloproteinases (MMP-3, MMP-13), and ADAMTS-4. The formula typically contains ingredients such as Phellodendri Chinensis Cortex, Anemarrhenae Rhizoma, and Rehmanniae Radix Praeparata.
- Brand names
- Hu-Qian Wan
- Other names
- Hidden Tiger PillHuqian Wan
02
Targets
ADAMTS4 (ADAM metallopeptidase with thrombospondin type 1 motif 4)IL1B (Interleukin-1 beta)IL-6 (Interleukin 6)MMP13 (Matrix metalloproteinase-13)MMP3 (Matrix metalloproteinase-3)TGM2 (Tissue Transglutaminase 2)IL1A (Interleukin 1 alpha)
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