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The 4th affiliated hospital of China Medical Univ. LSD1 compound L8

Development stage
Preclinical
Lead developer
The Fourth Hospital of China Medical University
01

Overview

The 4th affiliated hospital of China Medical Univ. LSD1 compound L8: sourced facts only. name: "Compound L8 as a selective and reversible LSD1 inhibitor could inhibit LSD1 with the IC50 value of 60 nM." [PMID:35350943]; target: "Compound L8 as a selective and reversible LSD1 inhibitor could inhibit LSD1 with the IC50 value of 60 nM." [PMID:35350943]; developer: "Department of Urology, The 4th affiliated hospital of China Medical University, Shenyang, PR China." [PMID:35350943]; stage: "sulphonamide derivative L8 exhibited the antiproliferative activity against HTB5, HTB3, HT1376, and HTB1 cells with IC50 values of 1.87, 0.18, 0.09, and 0.93 μM, respectively." [PMID:35350943]

02

Targets

KDM1A (LSD1)

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