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The Perfect Probiotics
- Development stage
- Phase 3
- Lead developer
- Seoul National University Bundang Hospital
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
The Perfect Probiotics is a multi-strain probiotic supplement primarily composed of *Lactobacillus acidophilus* and *Bifidobacterium lactis*. It is being investigated by Seoul National University Bundang Hospital as an adjunctive oral therapy for patients with neovascular age-related macular degeneration (nAMD). The treatment rationale is based on the potential modulation of the gut-retina axis; by altering the oral and intestinal microbiome, the supplement may influence systemic inflammatory pathways that contribute to the progression of choroidal neovascularization. In clinical pilot studies, it is administered orally in conjunction with standard-of-care intravitreal anti-VEGF injections to evaluate its impact on microbiome composition and clinical outcomes.
- Brand names
- The Perfect Probiotics
- Other names
- Probiotic Combination Cap/TabLactobacillus acidophilus + Bifidobacterium lactis
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