Drug intelligence / Profile preview

Theracurmin CR-031P

Development stage
Preclinical
Lead developer
Theravalues Corp
Modality
Small Molecules
Administration
Oral
01

Overview

Theracurmin CR-031P is a highly bioavailable curcumin formulation developed by Theravalues Corporation. It utilizes submicron particle technology and colloidal dispersion (using gum ghatti) to enhance the water dispersibility and oral absorption of curcumin, a polyphenol derived from turmeric (*Curcuma longa*). This formulation reportedly achieves 18-36 times higher bioavailability than standard curcumin powder. While marketed as a dietary supplement (brand name BIHOLON in Japan), it has been investigated in clinical settings for its anti-inflammatory and antioxidant effects in conditions such as cognitive decline, common cold symptoms, and as an adjunct in cancer immunotherapy.

Brand names
BIHOLONTheracurmin
Other names
curcuminturmeric extract
02

Targets

NF-κBTNFA (Tumor necrosis factor alpha (soluble))PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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