Drug intelligence / Profile preview

Theranekron

Development stage
Unknown
Lead developer
Richter Pharma
Administration
Subcutaneous, Intramuscular
01

Overview

Theranekron is a veterinary homeopathic preparation containing an alcoholic extract of the spider *Tarantula cubensis*. It is primarily utilized in veterinary medicine for the treatment of various inflammatory conditions, septic processes, and certain neoplastic diseases, such as mammary tumors in dogs and foot rot in cattle. The drug is thought to exert its therapeutic effects through immunomodulation and the induction of apoptosis in tumor cells. Research indicates that its mechanism of action involves the activation of the NKs/CTLs-GrzB-Casp10-Casp3 signaling pathway, leading to increased levels of Caspase-3, Caspase-10, and Granzyme-B, which facilitates programmed cell death. It is developed and manufactured by Richter Pharma and is often investigated as a potential adjunct to conventional chemotherapy in preclinical models.

Brand names
TheranekronTheranekron D6
Other names
Tarantula cubensis alcohol extractTarantula cubensis extract
02

Targets

CASP10 (Caspase-10)GZMB (Granzyme B)CASP3 (Caspase-3)

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