Drug intelligence / Profile preview

thiamine + folic acid

Development stage
Unknown
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Administration
Oral, Intravenous, Intramuscular
01

Overview

Thiamine + folic acid is a combination of two essential B vitamins—thiamine (vitamin B1) and folic acid (vitamin B9)—used primarily as a dietary supplement to prevent or treat deficiencies in these nutrients. Thiamine acts as a coenzyme in carbohydrate metabolism, supporting energy production and normal nerve function, while folic acid is crucial for DNA synthesis, cell division, and the formation of red blood cells. This combination may be used in various clinical settings such as nutritional supplementation for individuals with poor diet, certain illnesses, alcoholism, pregnancy, or increased requirements due to medical conditions[2]. Both components are water-soluble vitamins that must be obtained from the diet or supplements.

Other names
thiamine + folic acid
02

Targets

DHFR (Dihydrofolate reductase)NeuraminidaseTHTR (Thiamine transporter 1)

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