Drug intelligence / Profile preview

thiamine + pyridoxine + cyanocobalamin

Development stage
Phase 3
Lead developer
Grand Medical
Modality
Small Molecules
Administration
Intramuscular, Oral
01

Overview

Comfovita is a branded generic pharmaceutical product developed by Grand Medical Group, consisting of a combination of neurotropic B vitamins: thiamine (B1), pyridoxine (B6), and cyanocobalamin (B12). It is primarily indicated for the treatment of various neurological conditions, including neuritis, neuralgia, and polyneuropathy (such as diabetic or alcoholic neuropathy). The vitamins in Comfovita act as essential coenzymes in metabolic processes within the central and peripheral nervous systems, supporting nerve regeneration, myelin sheath formation, and neurotransmitter synthesis. Thiamine facilitates carbohydrate metabolism and nerve impulse conduction; pyridoxine is involved in the synthesis of neurotransmitters like dopamine and serotonin; and cyanocobalamin is critical for the synthesis of myelin and the maturation of red blood cells. The product is typically available as a solution for intramuscular injection or as oral tablets.

Brand names
Comfovita
Other names
Vitamin B1 + B6 + B12Neurotropic B vitamins
02

Targets

DDC (Aromatic L-amino acid decarboxylase)MTR (Methionine synthase)PDH E1 (Pyruvate dehydrogenase E1 component)

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