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thiamine + riboflavin + pyridoxine
- Development stage
- Unknown
- Lead developer
- Al-Madina Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
thiamine + riboflavin + pyridoxine is a fixed-dose combination of three essential water-soluble B-vitamins manufactured by Al-Madina Pharmaceuticals. This combination includes Thiamine (Vitamin B1), Riboflavin (Vitamin B2), and Pyridoxine (Vitamin B6), which serve as critical cofactors in numerous metabolic pathways. Thiamine is essential for carbohydrate metabolism and nerve function; Riboflavin is a precursor to the coenzymes FAD and FMN, which are vital for energy production and cellular respiration; and Pyridoxine is a precursor to pyridoxal 5'-phosphate (PLP), which is involved in amino acid metabolism, neurotransmitter synthesis, and hemoglobin formation. This product is marketed as a generic pharmaceutical in Bangladesh, primarily indicated for the prevention and treatment of vitamin B deficiencies and associated conditions such as peripheral neuropathy, beriberi, and ariboflavinosis.
- Other names
- Vitamin B1 + Vitamin B2 + Vitamin B6Thiamine Riboflavin PyridoxineVitamin B-complex (partial)
02
Targets
α-KGDH (Alpha-ketoglutarate dehydrogenase complex)PDH (Pyruvate dehydrogenase complex)GSR (Glutathione reductase)DDC (Aromatic L-amino acid decarboxylase)SDH (Mitochondrial electron transport chain complex II)TKT (Transketolase)
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