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thiamine hydrochloride + methylnicotinate
- Development stage
- Unknown
- Lead developer
- Sanofi
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
thiamine hydrochloride + methylnicotinate is a topical pharmaceutical combination used for the symptomatic relief of musculoskeletal pain, including myalgia, neuralgia, and joint pain. Methyl nicotinate acts as a rubefacient and potent vasodilator; upon topical application, it induces local hyperemia and a warming sensation that serves as a counter-irritant to alleviate deeper pain. Thiamine hydrochloride (Vitamin B1) is included to support local metabolic processes and nerve health. This combination is most notably marketed under the brand name Algipan in certain European markets, such as Italy, where it is indicated for various minor sports injuries and rheumatic conditions.
- Brand names
- Algipan
- Other names
- thiamine hydrochloridemethylnicotinatemethyl nicotinateVitamin B1 + methyl nicotinate
02
Targets
Thiamine pyrophosphate-dependent metabolic enzymesTPK1 (Thiamine pyrophosphokinase 1)
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