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Drug intelligence / Profile preview
thiamine hydrochloride + pyridoxine hydrochloride + cyanocobalamin
- Development stage
- Unknown
- Lead developer
- Sam-On
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Tribemin is a high-dose vitamin B complex formulation containing thiamine hydrochloride (Vitamin B1), pyridoxine hydrochloride (Vitamin B6), and cyanocobalamin (Vitamin B12). It is primarily indicated for the treatment of neuropathies, neuralgic lumbago, herpes zoster, and metabolic disorders. In clinical research, Tribemin has also been utilized as an active control/placebo in obstetric studies, such as trials evaluating the efficacy of propranolol for labor induction in post-term pregnancies or term premature rupture of membranes (PROM).
- Brand names
- Tribemin
- Other names
- cyanocobalamin + pyridoxine hydrochloride + thiamine hydrochloridethiamine + pyridoxine + cyanocobalaminvitamin B1 + vitamin B6 + vitamin B12
02
Targets
ADOR (Adenosine receptors)MTR (Methionine synthase)MMUT (Methylmalonyl-coenzyme A mutase)P2RX1 (Purinergic receptor P2X 1)NaV (Voltage-gated sodium channels)
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