Drug intelligence / Profile preview

Thiosalicylic acid

Development stage
Unknown
Modality
Small Molecules
Administration
Intramuscular, Intravenous, Topical, Oral
01

Overview

Thiosalicylic acid is an organosulfur compound with carboxyl and sulfhydryl functional groups. It acts as a non-narcotic analgesic and antipyretic, and is used (primarily as its sodium salt) to relieve symptoms of acute gout, painful musculoskeletal conditions, osteoarthritis, and rheumatic fever. Its mechanism of action involves inhibition of prostaglandin synthesis. Thiosalicylic acid has also been used as a precursor in the synthesis of other compounds such as the vaccine preservative thiomersal and the dyestuff thioindigo. It is associated with risks such as contact dermatitis[1][3][4][5].

Other names
thiosalicylic acid2-mercaptobenzoic acido-mercaptobenzoic acid2-thiosalicylic acido-thiosalicylic acid2-carboxythiophenolo-benzoic acid thiolo-carboxythiophenolo-sulfhydrylbenzoic acidbenzoic acid, 2-mercapto
02

Targets

Subclass B3 metallo-beta-lactamaseCOX-3 (Mitochondrially encoded cytochrome c oxidase subunit 3)

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