Drug intelligence / Profile preview

third-generation HPV vaccine

Development stage
Preclinical
Lead developer
Xiamen Innovax Biotech
Modality
Vaccines & Immunotherapeutics
01

Overview

The third-generation HPV vaccine is a **preclinical multivalent chimeric epitope HPV vaccine** being developed by **Xiamen Innovax Biotech** for prevention of **HPV-related diseases**, including **cervical cancer**. The candidate was designed using **structural vaccinology** principles to create a broad-spectrum, \"one-against-multi\" immunogen that incorporates neutralizing epitopes from multiple HPV types into chimeric constructs rather than using separate full virus-like particles for each type. It is produced on Innovax's proprietary **Escherichia coli expression platform** and is intended to elicit neutralizing antibody responses against HPV capsid epitopes with the goal of broad preventive efficacy across HPV-associated disease.

Other names
third-generation HPV vaccinemultivalent chimeric epitope HPV vaccinemulti-valent chimeric epitope HPV vaccine
02

Targets

HPV L1 (Human papillomavirus L1 capsid protein)

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