Drug intelligence / Profile preview

Thoracic Epidural Analgesia

Development stage
Unknown
Lead developer
Örebro University
Modality
Small Molecules
Administration
Epidural
01

Overview

Thoracic Epidural Analgesia (TEA) is a regional anesthetic technique involving the administration of medications into the epidural space at the thoracic level to provide targeted perioperative pain relief. In the clinical trial protocol developed by Örebro University for patients undergoing radical retropubic prostatectomy, the TEA intervention consists of an intra-operative administration of bupivacaine combined with adrenaline (epinephrine), followed by a post-operative infusion of ropivacaine and sufentanil. The technique is being investigated for its potential to modulate the immunological and inflammatory stress responses associated with major surgery. Research suggests that by attenuating the surgical stress response, TEA may potentially reduce cancer-related mortality and improve long-term outcomes in patients with prostate, breast, and colorectal cancers.

Other names
TEAThoracic Epidural AnesthesiaEpidural Analgesia
02

Targets

NaV (Voltage-gated sodium channels)MOR (Mu opioid receptor)ADRA1A (α1A)ADRB1 (β1)

Beyond the preview

Go deeper on Thoracic Epidural Analgesia.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Thoracic Epidural Analgesia.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call