Drug intelligence / Profile preview

Threonine

Development stage
Phase 3
Modality
Small Molecules
Administration
Oral, Enteral, Parenteral
01

Overview

Threonine is an indispensable (essential) amino acid, meaning it cannot be synthesized by the human body and must be obtained through diet. It serves as a fundamental building block for proteins, playing a critical role in various physiological processes. Notably, threonine is essential for the production of mucins, which are key proteins in the mucous membrane protecting the intestinal lining. It also contributes significantly to the formation of collagen, elastin, and tooth enamel. Deficiencies in threonine can impact small intestine growth and overall health. Its dietary requirements are being investigated across different populations, including healthy children, adults, the elderly, and individuals with conditions like Inflammatory Bowel Disease (IBD) and in infants.

Other names
L-threonine
02

Targets

aaRS (Aminoacyl-tRNA synthetase family)

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