Drug intelligence / Profile preview

thyme extract

Development stage
Phase 3
Administration
Oral, Topical, Inhalation
01

Overview

Thyme extract is derived from the leaves and aerial parts of the plant Thymus vulgaris or related thyme species. It is rich in **antioxidants** (including phenolic compounds like thymol, carvacrol, lutein, zeaxanthin, thymonin), **vitamins** (A, C, B6, K), and **minerals** (iron, calcium, magnesium, manganese)[1][5][7]. The extract exhibits **anti-inflammatory**, **antimicrobial**, **antiseptic**, and **expectorant** activities, with research showing action against bacteria, fungi, and viruses[2][3][5][7]. Thyme extract works by modulating inflammatory pathways—reducing cytokines TNF-α, IL-1β, IL-6—and boosting immune cytokine IL-10[7]. Its essential compounds, mainly thymol and carvacrol, disrupt microbial cell walls and neutralize free radicals[2][7]. Traditionally, thyme extract has been used for respiratory illnesses (bronchitis, cough, sore throat, asthma), digestive complaints (colic, upset stomach, indigestion), menstrual discomfort, oral/dental care, skin conditions (acne, eczema), and wound healing[1][3][5][6]. It is also used in food, cosmetics, and topical products. Scientific evidence remains mostly preclinical, with some proof in combination therapies for bronchitis and cough[6][7]. There is no single developer or manufacturer; it is produced by various supplement and herbal product companies.

Brand names
GeloBronchialGelo Bronchial
Other names
Thymus vulgaris extractthyme leaf extractthyme oil extractthyme tincture
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)IL1B (Interleukin-1 beta)IL-6 (Interleukin 6)NF-κBPPARA (Peroxisome proliferator-activated receptor alpha)PPARG (Peroxisome proliferator-activated receptor gamma)TNFA (Tumor necrosis factor alpha (soluble))NOS2 (Nitric Oxide Synthase 2)IL10 (Interleukin-10)

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