Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
TI-Inhalation Powder B
- Development stage
- Phase 4
- Lead developer
- Mannkind
- Modality
- Recombinant Proteins and Enzymes
- Administration
- Inhalation
01
Overview
TI-Inhalation Powder B refers to a specific formulation variant of Technosphere Insulin (TI) developed by MannKind Corporation. Technosphere Insulin, marketed under the brand name Afrezza, is an ultra-rapid-acting inhaled recombinant human insulin indicated for the treatment of type 1 and type 2 diabetes mellitus. The drug utilizes a proprietary dry-powder delivery system where insulin is adsorbed onto Technosphere microparticles composed of the excipient fumaryl diketopiperazine (FDKP). Upon inhalation, the powder dissolves rapidly in the neutral pH of the lung surface, allowing for systemic absorption that mimics the early-phase insulin release seen in healthy individuals. The 'Powder B' designation was specifically used in Phase 1 clinical trials to compare the pharmacokinetic and pharmacodynamic profiles of Technosphere Insulin manufactured using insulin from different suppliers.
- Brand names
- Afrezza
- Other names
- Technosphere InsulinInhaled InsulinRecombinant Human Insulin Inhalation Powder
02
Targets
INSR (Insulin receptor)
Beyond the preview
Go deeper on TI-Inhalation Powder B.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on TI-Inhalation Powder B.