Drug intelligence / Profile preview

tianwang buxin pill

Development stage
Unknown
Lead developer
Jinsheng Da Ren Tang
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Tian Wang Bu Xin Pill (also known as Tianwang Buxin Dan or Wan) is a classic traditional Chinese medicine (TCM) formula manufactured by Jinsheng Da Ren Tang (Tianjin Pharmaceutical Da Ren Tang Group) among other producers. It is formulated to nourish yin and blood, tonify the heart, and calm the spirit (Shen). The formula typically consists of a synergistic blend of multiple herbs, including *Rehmannia glutinosa*, *Angelica sinensis*, *Schisandra chinensis*, *Ziziphus jujuba*, *Platycladus orientalis*, *Asparagus cochinchinensis*, *Ophiopogon japonicus*, *Scrophularia ningpoensis*, *Salvia miltiorrhiza*, *Panax ginseng* (or *Codonopsis pilosula*), *Poria cocos*, *Platycodon grandiflorus*, and *Polygala tenuifolia*. It is widely approved and used in China for the treatment of insomnia, palpitations, anxiety, forgetfulness, and dream-disturbed sleep associated with heart and kidney yin deficiency.

Brand names
CalmHeartVigor
Other names
emperor's cardiotonic pillsemperor's teapillstian wang bu xin dantian wang bu xin piantian wang bu xin pilltian wang bu xin wantianwang buxin dantianwang buxin piantianwang buxin wan
02

Targets

IL1B (Interleukin-1 beta)DRD2 (Dopamine D2 Receptor)MAOA (Monoamine oxidase A)SERT (Sodium-dependent serotonin transporter)TPH2 (Tryptophan hydroxylase 2)IL-6 (Interleukin 6)

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