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Tiaogan Anshen is a traditional Chinese medicine (TCM) formulation, most commonly available as granules, used for the treatment of chronic insomnia. The name "Tiaogan" refers to "regulating the liver," and "Anshen" means "calming the spirit," reflecting its use in TCM theory to address sleep disturbances often attributed to liver dysfunction or emotional imbalance. The exact herbal composition may vary but typically includes a combination of herbs aimed at soothing the liver, relieving stress, and promoting restful sleep. Its mechanism of action is based on multi-herbal synergistic effects that modulate neurotransmitter systems and improve sleep quality; however, specific molecular targets are not well defined in Western pharmacological terms. Clinical studies have been conducted to evaluate its efficacy in patients with chronic insomnia[1].
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