Drug intelligence / Profile preview

tiaoganlipi prescription granules

Development stage
Unknown
Lead developer
Beijing Hospital of Traditional Chinese Medicine
Administration
Oral
01

Overview

Tiaoganlipi prescription granules is a Traditional Chinese Medicine (TCM) formulation developed by the Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University. It is primarily indicated for the treatment of gastroesophageal reflux disease (GERD) and its associated laryngopharyngeal reflux disease (LPRD). The prescription is based on the TCM therapeutic principle of "regulating the liver and strengthening the spleen" (Tiao Gan Li Pi) to address the underlying disharmony believed to cause reflux symptoms. In clinical trials, it is often administered as an oral granule in combination with proton pump inhibitors (PPIs) like omeprazole to enhance symptomatic relief and improve patient outcomes.

Other names
Tiaoganlipi prescriptionTiaoganlipi formulaTiaoganlipi prescription granules
02

Targets

MEK1 (Dual specificity mitogen-activated protein kinase kinase 1)CCNB1 (Cyclin B1)CCNA2 (Cyclin A2)ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase)IGF-1R (Insulin-like growth factor 1 receptor)EP300 (Histone acetyltransferase p300 (EP300) catalytic domain)CDK4 (Cyclin-dependent kinase 4)PR (Progesterone receptor)

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