Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
ticagrelor + clopidogrel
- Development stage
- Unknown
- Lead developer
- AstraZeneca
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
This entry refers to the comparative study of ticagrelor and clopidogrel in the context of the EndoTic clinical trial (NCT01952015), sponsored by the Fundación Investigación Sanitaria en León. Ticagrelor (Brilinta) is a direct-acting, reversible P2Y12 receptor antagonist, while clopidogrel (Plavix) is a thienopyridine prodrug that irreversibly inhibits the same receptor. Both are oral antiplatelet agents indicated for the reduction of thrombotic cardiovascular events in patients with acute coronary syndrome (ACS). The EndoTic trial specifically evaluates the pleiotropic effects of these treatments on the vascular endothelium, measuring changes in circulating endothelial cells (CECs) and endothelial progenitor cells (EPCs) over a one-month period.
- Brand names
- BrilintaPlavixBriliquePossiaIscover
- Other names
- ticagrelorclopidogrelEndoTic
02
Targets
P2Y12 (Purinergic P2Y12 receptor)
Beyond the preview
Go deeper on ticagrelor + clopidogrel.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on ticagrelor + clopidogrel.