Drug intelligence / Profile preview

Tick-Vac

Development stage
Unknown
Lead developer
LIMOR laboratory
Modality
Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Administration
Subcutaneous
01

Overview

Tick-Vac is a veterinary vaccine developed by LIMOR (Laboratorios Limor de Colombia) for the control of infestations by the cattle tick, *Rhipicephalus (Boophilus) microplus*. The vaccine is based on recombinant protein technology, typically utilizing the Bm86 midgut antigen. When administered to cattle, it stimulates the production of specific antibodies in the host. As ticks feed on the vaccinated animal, these antibodies are ingested and subsequently bind to the tick's midgut cells, causing significant structural damage to the digestive tract. This interference leads to a reduction in the tick's reproductive capacity, including decreased egg laying and larval viability, as well as increased adult mortality. Tick-Vac is utilized as part of an integrated pest management strategy to reduce the environmental impact of chemical acaricides and combat tick resistance in livestock management.

Brand names
Tick-Vac
Other names
vacuna contra la garrapata
02

Targets

Bm86 (Bm86 gut surface glycoprotein)

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