Drug intelligence / Profile preview

ticlopidine + ginkgo biloba extract

Development stage
Unknown
Lead developer
Yuyu Pharma
Modality
Small Molecules
Administration
Oral
01

Overview

**Ticlopidine + ginkgo biloba extract** is an oral fixed-dose antiplatelet combination marketed by Yuyu Pharma as **Yuclid**. Each film-coated tablet contains ticlopidine hydrochloride 250 mg and Ginkgo biloba extract 80 mg. Ticlopidine is a thienopyridine prodrug whose active metabolite irreversibly inhibits platelet P2Y12 signaling, thereby suppressing ADP-mediated platelet activation and aggregation; the standardized Ginkgo biloba extract provides complementary, multi-constituent antiplatelet and antioxidant activity. In South Korea, Yuclid is approved as an alternative to concomitant ticlopidine plus Ginkgo biloba extract therapy for chronic arterial insufficiency, ischemic cerebrovascular disease including transient ischemic attack and cerebral infarction, coronary artery disease, and prevention of subacute coronary-stent thrombosis. ([yuyu.co.kr](https://yuyu.co.kr/en/productInfo/productView/13/))

Brand names
Yuclid유크리드
Other names
ticlopidine + ginkgo bilobaticlopidine + ginkgo biloba extractticlopidine hydrochloride + ginkgo biloba extractticlopidine/ginkgo biloba extract
02

Targets

P2Y12 (Purinergic P2Y12 receptor)PTAFR (Platelet-activating factor receptor)

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