Drug intelligence / Profile preview

tieghemella heckelii aqueous leaf extract

Development stage
Preclinical
Modality
Small Molecules
01

Overview

Tieghemella heckelii aqueous leaf extract is a botanical preparation derived from the leaves of the Tieghemella heckelii tree, a species native to West and Central Africa often referred to as Baku or Cherry Mahogany. While the stem bark of this plant has a history of use in traditional medicine, recent scientific research has explored the anticancer potential of its leaves. In vitro studies have demonstrated that the aqueous extract exhibits significant cytotoxic activity against several human cancer cell lines, including breast (MDA-MB-468), liver (HepG2), and prostate (PC3) cancer. The extract is believed to contain bioactive phytochemicals that induce cell death or inhibit proliferation, though the specific active compounds and their precise molecular mechanisms of action are still being investigated.

Other names
Tieghemella heckelii leaf extractBaku leaf extract

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