Drug intelligence / Profile preview

tiepifengdou granules

Development stage
Phase 2
Lead developer
The Chinese University of Hong Kong
Administration
Oral
01

Overview

**Tiepifengdou granules** are an oral traditional Chinese medicine herbal combination containing *Dendrobium officinale* and *Panax quinquefolius*. The product is used in traditional Chinese medicine to nourish qi and yin and support gastric fluid production. It is manufactured by Zhejiang Tianhuang Pharmaceutical and is marketed in China as an OTC Chinese patent medicine. Clinical development has included randomized placebo-controlled studies for chronic atrophic gastritis with qi-yin deficiency, including a completed Chinese phase 3 trial. Its molecular pharmacology has not been established as a defined single-target mechanism. ([pharnexcloud.com](https://www.pharnexcloud.com/data/lcsy_25208ecb79eb1f8e1444fdf915e97673.html))

Other names
Granules DendrobiiDendrobii granulesGrannle Dendrobii granules铁皮枫斗颗粒Tiepi Fengdou Granules
02

Targets

BCL-2 (BCL-2 family)NCOA1 (Nuclear receptor coactivator 1)STAT3 (Signal Transducer and Activator of Transcription 3)TNFA (Tumor necrosis factor alpha (soluble))MAOA (Monoamine oxidase A)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)PPARG (Peroxisome proliferator-activated receptor gamma)

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