Drug intelligence / Profile preview

timolol + brimonidine + dorzolamide + brinzolamide

Development stage
Unknown
Lead developer
Laboratorios Sophia
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

A hypothetical quadruple combination of ophthalmic medications including timolol (a beta-blocker), brimonidine (an alpha-2 adrenergic agonist), and two carbonic anhydrase inhibitors (dorzolamide and brinzolamide). This exact combination does not appear to exist as a single commercial product. These agents work through different mechanisms to reduce intraocular pressure in patients with glaucoma or ocular hypertension.

02

Targets

ADRB1 (β1)CA2 (Carbonic Anhydrase 2)ADRA2A (α2A)

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