Drug intelligence / Profile preview

timolol maleate gel + placebo

Development stage
Unknown
Lead developer
Alembic Pharmaceuticals
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

Timolol maleate gel is a non-selective beta-adrenergic receptor blocking agent used in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. When applied topically on the eye, it forms a gel in the precorneal tear film that is subsequently removed by the flow of tears. The precise mechanism of the ocular hypotensive action is not clearly established, but studies suggest it may be related to reduced aqueous formation. The placebo component indicates this is likely a clinical trial formulation where timolol maleate gel is being compared with a placebo control.

Brand names
Timoptic-XE
Other names
Timolol Maleate Ophthalmic Gel Forming Solution
02

Targets

ADRB2 (β2)ADRB1 (β1)

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